| Round | Date | Grand Prix | Circuit |
| 1 | 26-Mar | Grand Prix of Qatar | Losail International Circuit, Lusail |
| 2 | 9-Apr | Gran Premio Motul de la República Argentina |
Autódromo Termas de Río Hondo, Santiago del Estero |
| 3 | 23-Apr | Red Bull Grand Prix of the Americas |
Circuit of the Americas, Austin |
| 4 | 7-May | Gran Premio Red Bull de España |
Circuito de Jerez, Jerez de la Frontera |
| 5 | 21-May | HJC Helmets Grand Prix de France |
Circuit Bugatti, Le Mans |
| 6 | 4-Jun | Gran Premio d’Italia | Mugello Circuit, Scarperia |
| 7 | 11-Jun | Gran Premi Monster Energy de Catalunya |
Circuit de Barcelona-Catalunya, Montmeló |
| 8 | 25-Jun | Motul TT Assen | TT Circuit Assen, Assen |
| 9 | 2-Jul | GoPro Motorrad Grand Prix Deutschland |
Sachsenring, Hohenstein-Ernstthal |
| 10 | 6-Aug | Monster Energy Grand Prix České republiky |
Automotodrom Brno, Brno |
| 11 | 13-Aug | NeroGiardini Motorrad Grand Prix von Österreich |
Red Bull Ring, Spielberg |
| 12 | 27-Aug | Octo British Grand Prix | Silverstone Circuit, Silverstone |
| 13 | 10-Sep | Gran Premio di San Marino e della Riviera di Rimini |
Misano World Circuit Marco Simoncelli, Misano Adriatico |
| 14 | 24-Sep | Gran Premio Movistar de Aragón | Motorland Aragón, Alcañiz |
| 15 | 15-Oct | Motul Grand Prix of Japan | Twin Ring Motegi, Motegi |
| 16 | 22-Oct | Australian Motorcycle Grand Prix |
Phillip Island Grand Prix Circuit, Phillip Island |
| 17 | 29-Oct | Shell Malaysia Motorcycle Grand Prix |
Sepang International Circuit, Selangor |
| 18 | 12-Nov | Gran Premio Motul de la Comunitat Valenciana |
Circuit Ricardo Tormo, Valencia |
