Provisional riders and teams have been announced for the MotoGP class in 2018
| # | RIDER | NATIONALITY | TEAM | MACHINE |
| 4 | ANDREA DOVIZIOSO | ITALIAN | DUCATI TEAM | DUCATI |
| 5 | JOHANN ZARCO | FRENCH | MONSTER YAMAHA TECH 3* | YAMAHA |
| 9 | DANILO PETRUCCI | ITALIAN | OCTO PRAMAC RACING* | DUCATI |
| 10 | XAVIER SIMEON | BELGIAN | REALE AVINTIA RACING* | DUCATI |
| 12 | TOM LUTHI | SWISS | EG 0,0 MARC VDS* | HONDA |
| 17 | KAREL ABRAHAM | CZECH | PULL&BEAR ASPAR TEAM* | DUCATI |
| 19 | ALVARO BAUTISTA | SPANISH | PULL&BEAR ASPAR TEAM* | DUCATI |
| 21 | FRANCO MORBIDELLI | ITALIAN | EG 0,0 MARC VDS* | HONDA |
| 25 | MAVERICK VIÑALES | SPANISH | MOVISTAR YAMAHA MotoGP | YAMAHA |
| 26 | DANI PEDROSA | SPANISH | REPSOL HONDA TEAM | HONDA |
| 29 | ANDREA IANNONE | ITALIAN | TEAM SUZUKI ECSTAR | SUZUKI |
| 30 | TAKAAKI NAKAGAMI | JAPANESE | LCR HONDA IDEMITSU* | HONDA |
| 35 | CAL CRUTCHLOW | BRITISH | LCR HONDA CASTROL* | HONDA |
| 38 | BRADLEY SMITH | BRITISH | RED BULL KTM FACTORY RACING | KTM |
| 41 | ALEIX ESPARGARO | SPANISH | APRILIA RACING TEAM GRESINI* | APRILIA |
| 42 | ALEX RINS | SPANISH | TEAM SUZUKI ECSTAR | SUZUKI |
| 43 | JACK MILLER | AUSTRALIAN | OCTO PRAMAC RACING* | DUCATI |
| 44 | POL ESPARGARO | SPANISH | RED BULL KTM FACTORY RACING | KTM |
| 45 | SCOTT REDDING | BRITISH | APRILIA RACING TEAM GRESINI* | APRILIA |
| 46 | VALENTINO ROSSI | ITALIAN | MOVISTAR YAMAHA MotoGP | YAMAHA |
| 53 | TITO RABAT | SPANISH | REALE AVINTIA RACING* | DUCATI |
| 93 | MARC MARQUEZ | SPANISH | REPSOL HONDA TEAM | HONDA |
| 94 | JONAS FOLGER | GERMAN | MONSTER YAMAHA TECH 3* | YAMAHA |
| 99 | JORGE LORENZO | SPANISH | DUCATI TEAM | DUCATI |
| * = INDEPENDENT TEAM |